Cataracts affect 25 million people in the U.S., and these numbers are expected to rise as Americans age and life expectancy increases. A subtle chemical change in an eye lens protein can make the protein more likely to clump together over time, suggesting an early step in cataract formation according to a new study from UC Irvine researchers. “What surprised us is that the protein can still look mostly normal, but even a small chemical change makes it much more likely to stick to other proteins,” said Yeonseong (Catherine) Seo, lead author and Ph.D. candidate in chemistry. “Over time, those small interactions can add up and cloud the lens.” The National Institute of Health supported the work. #SpeakUp4Science